About the Role
Discover International is partnering with a growing pharmaceutical company to recruit a highly skilled Organic Chemist.
This is a hands-on position for a rigorous synthetic chemist who can take ownership of challenging chemistry, design practical synthetic routes and independently troubleshoot reactions through to a successful outcome. The successful candidate will contribute directly to novel drug candidates within the company’s internal pipeline.
Responsibilities
- Design and execute complex, multistep small-molecule syntheses
- Develop and synthesize metal chelators, fluorophores, linkers and related conjugates
- Troubleshoot difficult reactions independently using a first-principles scientific approach
- Optimize reaction conditions, purification methods, yields and reproducibility
- Characterize compounds using techniques including NMR, LC-MS and HPLC
- Maintain accurate experimental records and communicate results clearly
- Support process development, scale-up and technology transfer activities
- Collaborate across discovery, development and manufacturing
- Remain actively involved at the laboratory bench
Qualifications
- PhD in Organic Chemistry, Medicinal Chemistry or a closely related discipline preferred
- Strong hands-on experience in synthetic organic chemistry
- Demonstrated experience designing or synthesizing metal chelators
- Demonstrated experience in fluorophore or fluorescent-probe chemistry, ideally including bioconjugation
- Proven ability to solve difficult synthetic and purification problems independently
- Experience with complex multistep synthesis and route development
- Strong analytical, organizational and scientific communication skills